Folic acid is one of the essential vitamins, particularly for women who plan to become pregnant. Folate is an essential part of a woman’s diet and is vital in the prevention of serious birth defects. It can be obtained in the form of fortified foods or vitamins. Natural sources of foliate include leafy green vegetables, oranges, beans and fruits. But if you’re planning to get pregnant, you may want to get more information about foliate.
Folic acid is essential for fetal development
Folic acid, also known as vitamin B9, is a nutrient that plays a crucial role in the fetal development of the neural tube. The neural tube develops the brain and spinal cord within four to six weeks after conception. When the neural tube does not develop correctly, the baby is likely to be born with a serious birth defect known as neural tube defect (NTD). These defects can cause severe disabilities for the baby, including paralysis or multiple surgeries. Women who are diabetic, pregnant, or take other medications should consult with their physician before trying to conceive. Genetic mutations such as MTHFR may also increase the risk of developing NTDs.
For women who want to be proactive about the health of their children, it is important to supplement with vitamins that contain folic acid. Most multivitamins contain 400 mcg of folic acid per day. However, prenatal vitamins contain the precise amount of folic acid needed to develop a healthy fetus. Taking prenatal vitamins before conception is important for many reasons, but many women don’t bother with this. セルノスジェル for healthy health and boost your immunity, this is the one you need.
It prevents neural tube defects
In addition to preventing birth defects, folic acid can also lower a woman’s risk of heart disease and certain types of cancer. A new study suggests that a woman taking 400 micrograms of folic acid per day before conception may prevent up to 80% of neural tube defects. It’s important to take folic acid, which is naturally found in foods like spinach, broccoli, kale, and bananas.
While this recommendation is applicable to all women of childbearing age, it doesn’t apply to women who have already had children with neural tube defects. Women at high risk for this condition should consume higher doses of folic acid. The CDC offers free information and educational materials on folic acid and how to take it. To find out if folic acid is right for you, visit the website of the Centers for Disease Control and Prevention (CDC).
It helps reverse the toxic effects of methotrexate
One of the side effects of the cancer drug methotrexate is a decrease in folate levels. Methotrexate blocks the enzyme DHFR, which is responsible for converting folic acid into tetrahydrofolic acid. Tetrahydrofolate is essential for the biosynthesis of thymidylate and purine nucleotides. The drugs affect the synthesis of nucleic acids, which interferes with the synthesis and repair of DNA and cellular replication. Folate helps reverse these effects by increasing the folate levels in the body.
It was found that folic acid could reverse the toxic effects of methotrexates. A study published in 2004 evaluated the effectiveness of folic acid in patients treated with methotrexate. Researchers assigned 79 patients with rheumatoid arthritis to either a placebo or 5 or 27.5 mg of folic acid once a week. The participants were assessed for duration of toxic events and clinical severity. Plasma and erythocyte folate levels were also assessed.
It improves arterial endothelial function
In a recent study, folic acid supplementation was found to improve arterial endothelial function. In addition to decreasing plasma homocysteine, folic acid also decreased plasma levels of creatinine and glucose. These results suggest that folic acid may have important implications for the prevention of atherosclerosis in patients with hyperhomocysteinemia. The authors thank Dr. A.S. Burbage for donating the folic acid and matched placebo, and Dr. Z.E. Clark for providing the homocysteine.
The present study analyzed eight randomized trials that assessed the effects of folic acid on coronary artery disease. Of these, two studies were excluded because of imprecise information. The remaining six trials were included in the meta-analysis. The studies were reviewed by two independent authors, and disagreements were resolved through discussion and joint assessment with a third reviewer.
It relieves depression
Folic acid is a vitamin that helps build the essential neurotransmitters serotonin, norepinephrine, and dopamine, which are believed to be depleted in depression. Folic acid is not the active ingredient in these supplements, but the related form 5-MTHF is used in prescription medical foods. While there are also nonprescription products that contain optimized forms of folate, these should be avoided. Instead, look for supplements with methylfolate, or GABA, which are both neurotransmitters that can help relieve stress and depression. シアリス ジェネリック are helpful to reduce ED.
Many people take folic acid in the form of a synthetic form. It works by affecting the production of neurotransmitters, called monoamines. Folic acid is available in tablet or capsule form and is highly recommended for depression patients. Folic acid has been shown to reduce depressive symptoms and anxiety. Folate is found to help prevent neural tube defects in children. Folate can also help improve a person’s immune system.